Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602302 | 0.93 | GHSR (0.42) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL6599917 | 0.92 | GHSR (0.43) | GHSRTACR1MMP9MMP8 | |
| SCHEMBL3726874 | 0.92 | MMP9 (0.40) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL13808414 | 0.92 | MMP9 (0.40) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL13808413 | 0.92 | MMP9 (0.40) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL6600613 | 0.87 | GHSR (0.46) | GHSRTACR1MMP9MMP8 | |
| SCHEMBL6602261 | 0.82 | GHSR (0.41) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL5158806 | 0.82 | F2 (0.42) | TACR1MMP9MMP8FCER2 | |
| SCHEMBL5158813 | 0.82 | F2 (0.42) | TACR1MMP9MMP8FCER2 | |
| SCHEMBL6602122 | 0.81 | MC4R (0.42) | GHSRTACR1MMP9MMP8FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |