Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | FCER2 | P06734 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600377 | 0.89 | CTSS (0.50) | CTSBCTSSCTSKMEN1KMT2A | |
| SCHEMBL6602302 | 0.89 | GHSR (0.42) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL6603214 | 0.87 | CTSB (0.41) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL6603208 | 0.87 | CTSB (0.41) | GHSRCTSBCTSSCTSKPTPN1 | |
| SCHEMBL6601286 | 0.82 | GHSR (0.44) | GHSRTACR1MMP9MMP8FCER2 | |
| SCHEMBL6599917 | 0.80 | GHSR (0.43) | GHSRTACR1MMP9MMP8 | |
| SCHEMBL27493491 | 0.80 | CTSS (0.53) | CTSBCTSSCTSKPTPN1TACR1 | |
| SCHEMBL6604204 | 0.80 | CTSS (0.53) | CTSBCTSSCTSKPTPN1TACR1 | |
| SCHEMBL27479002 | 0.79 | CTSS (0.43) | CTSBCTSSCTSKMEN1KMT2A | |
| SCHEMBL13808413 | 0.79 | MMP9 (0.40) | GHSRCTSBCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |