Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.54 |
| ▸ | ITGAL | P20701 | 7/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605147 | 0.78 | PGR (0.43) | PGRITGALITGB2ICAM1PIK3CD | |
| SCHEMBL13735589 | 0.73 | PGR (0.65) | PGRITGALITGB2ICAM1PIK3CD | |
| SCHEMBL3010046 | 0.71 | PGR (0.68) | PGRPIK3CDEPHX2 | |
| SCHEMBL6013854 | 0.70 | PGR (1.00) | PGRPIK3CDEPHX2 | |
| SCHEMBL19241189 | 0.69 | ITGAL (0.43) | PGRITGALITGB2ICAM1 | |
| SCHEMBL19410676 | 0.68 | PGR (0.62) | PGRPIK3CDEPHX2 | |
| SCHEMBL31220002 | 0.68 | MEN1 (0.44) | HTR6 | |
| SCHEMBL6600515 | 0.68 | PGR (0.47) | PGRITGAL | |
| SCHEMBL31220147 | 0.67 | MEN1 (0.46) | HTR6 | |
| SCHEMBL3016234 | 0.65 | PGR (0.77) | PGRPIK3CDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399155-A4 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1399155-A2 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2001006984-A2 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |