Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976213 | 1.00 | ALOX5 (0.31) | ALOX5AKT1NR1I2IRAK4 | |
| SCHEMBL6987008 | 0.85 | — | — | |
| SCHEMBL20819448 | 0.84 | ALOX5 (0.41) | ALOX5AKT1NR1I2 | |
| SCHEMBL20819447 | 0.84 | ALOX5 (0.41) | ALOX5AKT1NR1I2 | |
| SCHEMBL660010 | 0.83 | — | — | |
| SCHEMBL27478815 | 0.83 | — | — | |
| SCHEMBL8712759 | 0.81 | ALOX5 (0.33) | ALOX5AKT1NR1I2 | |
| SCHEMBL656620 | 0.81 | — | — | |
| SCHEMBL27364976 | 0.81 | AKT1 (0.32) | AKT1 | |
| SCHEMBL8717018 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957069-B2 | Benzofuran derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-17 | — | — | US | disclosed |
| EP-2781513-A1 | Benzofuran derivatives | Takeda Pharmaceutical Company Limited (JP) | 2014-09-24 | — | — | EP | disclosed |
| EP-2406243-B1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8288390-B2 | Benzofuran derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120232095-A1 | BENZOFURAN DERIVATIVES | TSUKAMOTO TETSUYA (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120232096-A1 | BENZOFURAN DERIVATIVES | TSUKAMOTO TETSUYA (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120046277-A1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-2406243-A1 | BENZOFURAN DERIVATIVES | Takeda Pharmaceutical Company Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20100234357-A1 | Benzofuran derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| WO-2010104194-A1 | BENZOFURAN DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | WO | disclosed |
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| US-7553837-B2 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-7553837-B2 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-7553837-B2 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20060247228-A1 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| US-20060189673-A1 | Phenylazole compound, production process therefor and antioxidant | NIPPON SODA CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1650206-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS, AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1614688-A1 | PHENYLAZOLE COMPOUND, PRODUCTION PROCESS, AND ANTIOXIDANT DRUG | NIPPON SODA CO., LTD. (JP) | 2006-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232096-A1 | BENZOFURAN DERIVATIVES | AHR, BRPF3, CBR3 | ALOX5 953/4885AKT1 2681/4885NR1I2 61/4885 |
| US-20100234357-A1 | Benzofuran derivatives | AHR, BRPF3, CBR3 | ALOX5 953/4885AKT1 2681/4885NR1I2 61/4885 |
| US-20120232095-A1 | BENZOFURAN DERIVATIVES | AHR, BRPF3, CBR3 | ALOX5 953/4885AKT1 2681/4885NR1I2 61/4885 |
| US-20090306055-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS | NOX1, CBR1, AOX1 | ALOX5 961/4885AKT1 2218/4885NR1I2 273/4885 |
| US-20060247228-A1 | Phenylazole compounds production process and antioxidants | CBR1, CBR3, NOX3 | ALOX5 934/4885AKT1 2465/4885NR1I2 353/4885 |
| US-20060189673-A1 | Phenylazole compound, production process therefor and antioxidant | CBR3, CYP4F11, CBR1 | ALOX5 429/4885AKT1 1246/4885NR1I2 1823/4885 |
| US-20120046277-A1 | BENZOFURAN DERIVATIVES | BRPF3, BRD1, CBR3 | ALOX5 1982/4885AKT1 2049/4885NR1I2 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.