SCHEMBL660191

SCHEMBL660191

CCOC(=C([SiH3])c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
MAPT P10636 3/20 0.43
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
RAB9A P51151 2/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 1/20 0.39
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831789 0.84 MEN1 (0.43) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL27879907 0.83 KMT2A (0.48) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL5831784 0.82 MEN1 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL1608024 0.79 KMT2A (0.46) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL9310847 0.79 MEN1 (0.46) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL11807023 0.79 TSHR (0.47) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL3309374 0.77 TSHR (0.46) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL19858501 0.75 CES2 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL4739425 0.74 KMT2A (0.50) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL660190 0.73 MEN1 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240401204-A1 METHOD AND COMPOSITION FOR ADJUSTING HYDROPHILICITY OF METAL USING A POLYPHENOL AND A SILANE MODIFIED NANO PARTICULATE OR AMINO ACID AMND SILICA Bulk Chemicals (US) 2024-12-05 US claimed
US-20120045772-A1 Affinity Hydrogel and Label Independent Detection Methods Thereof CORNING INCORPORATED 2012-02-23 US claimed
EP-2362220-A1 Affinity hydrogel and label independent detection methods thereof Corning Incorporated (US) 2011-08-31 EP claimed
US-20240401204-A1 METHOD AND COMPOSITION FOR ADJUSTING HYDROPHILICITY OF METAL USING A POLYPHENOL AND A SILANE MODIFIED NANO PARTICULATE OR AMINO ACID AMND SILICA Bulk Chemicals (US) 2024-12-05 US disclosed
EP-2220176-B1 SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION DUBLIN INSTITUTE OF TECH INTELLECTUAL PROPERTY LTD (IE) 2018-09-19 EP disclosed
US-8460923-B2 Affinity hydrogel and label independent detection methods thereof CORNING INCORPORATED (US) 2013-06-11 US disclosed
US-20120045772-A1 Affinity Hydrogel and Label Independent Detection Methods Thereof CORNING INCORPORATED 2012-02-23 US disclosed
EP-2362220-A1 Affinity hydrogel and label independent detection methods thereof Corning Incorporated (US) 2011-08-31 EP disclosed
US-20100330380-A1 Organosilane Coating Compositions and Use Thereof DUBLIN CITY UNIVERSITY (IE) 2010-12-30 US disclosed
EP-2220176-A2 SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION Dublin Institute of Technology Intellectual Property Ltd (IE) 2010-08-25 EP disclosed
WO-2009069111-A2 SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION DUBLIN INSTITUTE OF TECHNOLOGY (IE) 2009-06-04 WO disclosed