SCHEMBL5831789

SCHEMBL5831789

CCOC([SiH3])=C(OCC)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
MAPT P10636 3/20 0.43
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
GAA P10253 2/20 0.39
RAB9A P51151 1/20 0.39
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL660191 0.84 MEN1 (0.43) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL27879907 0.83 KMT2A (0.48) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL19858501 0.83 CES2 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL660190 0.82 MEN1 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL11807023 0.79 TSHR (0.47) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL9310847 0.79 MEN1 (0.46) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL1608024 0.79 KMT2A (0.46) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL4739425 0.74 KMT2A (0.50) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL5831784 0.73 MEN1 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL6144651 0.73 ALDH1A1 (0.53) MEN1KMT2AMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894935-A Phosphorus-containing vinyl polysiloxane and preparation method and application thereof 江南大学 2023-04-04 CN claimed
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-05-13 US disclosed
US-20240166778-A1 METHOD FOR PRODUCING POLYMER AND POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-23 US disclosed
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-08-03 US disclosed
EP-3590596-B1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-07-12 EP disclosed
CN-115894935-A Phosphorus-containing vinyl polysiloxane and preparation method and application thereof 江南大学 2023-04-04 CN disclosed
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-12-22 US disclosed
CN-110366449-B Catalyst for hydrosilylation, hydrogenation, and hydrosilane reduction 国立大学法人九州大学 2022-10-21 CN disclosed
EP-3406616-B1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
US-20200165274-A1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-28 US disclosed
CN-111132990-A Cobalt complex, process for producing the same, and catalyst for hydrosilylation 国立大学法人九州大学 2020-05-08 CN disclosed
US-10316046-B2 Method for producing acyloxysilanes, acyloxysilanes obtained thereby, and use of same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-11 US disclosed
EP-3406616-A1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST Shin-Etsu Chemical Co., Ltd. (JP) 2018-11-28 EP disclosed
US-20180044359-A1 Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2018-02-15 US disclosed
US-7081503-B2 Process producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition KANEKA CORPORATION (JP) 2006-07-25 US disclosed
US-7009004-B2 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2006-03-07 US disclosed
US-20060004171-A1 Process for producing vinyl polymer having alkenyl group at end, vinyl polymer, and curable composition TSUJI RYOTARO 2006-01-05 US disclosed
US-20040097678-A1 Process for producing vinyl polymer having alkenyl group at end vinyl polymer and curable composition KANEKA CORPORATION (JP) 2004-05-20 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction H1-0, HVCN1, H1-2 MEN1 441/4885KMT2A 1314/4885MAPT 4498/4885
US-20200165274-A1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST IDH1, IDH2, IDH3A MEN1 223/4885KMT2A 682/4885MAPT 3564/4885
US-20180044359-A1 Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same COASY, AGPS, CA7 MEN1 1859/4885KMT2A 1042/4885MAPT 4750/4885
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 MEN1 441/4885KMT2A 1314/4885MAPT 4498/4885
US-10316046-B2 Method for producing acyloxysilanes, acyloxysilanes obtained thereby, and use of same COASY, AGPS, CA7 MEN1 1859/4885KMT2A 1042/4885MAPT 4750/4885
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 MEN1 439/4885KMT2A 1306/4885MAPT 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.