SCHEMBL660190

SCHEMBL660190

CCOC([SiH3])=C(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
MAPT P10636 3/20 0.44
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP19A1 P11511 3/20 0.42
LMNA P02545 1/20 0.41
PTGS2 P35354 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
ESR1 P03372 2/20 0.40
GAA P10253 2/20 0.40
ESR2 Q92731 1/20 0.40
RAB9A P51151 1/20 0.40
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831789 0.82 MEN1 (0.43) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL3309368 0.76 TSHR (0.48) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL662841 0.75 MEN1 (0.45) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL5831784 0.75 MEN1 (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL9041640 0.74 ALDH1A1 (0.47) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL1641519 0.74 ALDH1A1 (0.47) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL660191 0.73 MEN1 (0.43) MEN1KMT2AMAPTNPC1ALDH1A1
Toluene SCHEMBL28234434 0.73 TSHR (0.44) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL2504896 0.73 CYP2D6 (0.43) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL796953 0.73 TSHR (0.52) MEN1KMT2AMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240401204-A1 METHOD AND COMPOSITION FOR ADJUSTING HYDROPHILICITY OF METAL USING A POLYPHENOL AND A SILANE MODIFIED NANO PARTICULATE OR AMINO ACID AMND SILICA Bulk Chemicals (US) 2024-12-05 US claimed
US-20120045772-A1 Affinity Hydrogel and Label Independent Detection Methods Thereof CORNING INCORPORATED 2012-02-23 US claimed
EP-2362220-A1 Affinity hydrogel and label independent detection methods thereof Corning Incorporated (US) 2011-08-31 EP claimed
EP-1172823-B1 Porous materials SHIPLEY CO LLC (US) 2007-11-28 EP claimed
US-20250033983-A1 METHOD FOR MAKING HOLLOW SILICA PARTICLES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-01-30 US disclosed
US-20240401204-A1 METHOD AND COMPOSITION FOR ADJUSTING HYDROPHILICITY OF METAL USING A POLYPHENOL AND A SILANE MODIFIED NANO PARTICULATE OR AMINO ACID AMND SILICA Bulk Chemicals (US) 2024-12-05 US disclosed
US-12139411-B2 Hydrolytic and calcination method for forming hollow silica particles IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-11-12 US disclosed
US-12102718-B2 Multistage calcination method for making hollow silica spheres IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-10-01 US disclosed
US-12102716-B2 Method for making solid silica spheres IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-10-01 US disclosed
US-12102717-B2 Hollow silica spheres with nested iron oxide particles IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-10-01 US disclosed
US-20240294387-A1 HYDROLYTIC AND CALCINATION METHOD FOR FORMING HOLLOW SILICA PARTICLES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-09-05 US disclosed
US-20240216279-A1 MULTISTAGE CALCINATION METHOD FOR MAKING HOLLOW SILICA SPHERES IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-07-04 US disclosed
EP-2220176-B1 SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION DUBLIN INSTITUTE OF TECH INTELLECTUAL PROPERTY LTD (IE) 2018-09-19 EP disclosed
US-8460923-B2 Affinity hydrogel and label independent detection methods thereof CORNING INCORPORATED (US) 2013-06-11 US disclosed
US-20120045772-A1 Affinity Hydrogel and Label Independent Detection Methods Thereof CORNING INCORPORATED 2012-02-23 US disclosed
EP-2362220-A1 Affinity hydrogel and label independent detection methods thereof Corning Incorporated (US) 2011-08-31 EP disclosed
US-20100330380-A1 Organosilane Coating Compositions and Use Thereof DUBLIN CITY UNIVERSITY (IE) 2010-12-30 US disclosed
EP-2220176-A2 SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION Dublin Institute of Technology Intellectual Property Ltd (IE) 2010-08-25 EP disclosed
WO-2009069111-A2 SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION DUBLIN INSTITUTE OF TECHNOLOGY (IE) 2009-06-04 WO disclosed
WO-2009051443-A2 PHOTOACTIVE COMPOSITION COMPRISING SCORIA AND PREPARATION METHOD THEREOF NURIDLE CO., LTD. (KR) 2009-04-23 WO disclosed