Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607856 | 0.83 | MAPT (0.45) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6604726 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6607045 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6606958 | 0.77 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6602596 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2MAPTPTGS1 | |
| SCHEMBL6606961 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6607136 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2MAPTPTGS1 | |
| SCHEMBL8369082 | 0.73 | PPARG (0.43) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6603316 | 0.70 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL6376052 | 0.70 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020453-B1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERIVATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6348461-B1 | CENTRAL NERVOUS SYSTEM ANTAGONIST WITH HETEROCYCLIC SUBSTITUENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1020453-A1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERI VATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |