Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 15/20 | 0.49 |
| ▸ | NOS1 | P29475 | 17/20 | 0.48 |
| ▸ | NOS2 | P35228 | 12/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602083 | 1.00 | NOS3 (0.49) | NOS3NOS1NOS2 | |
| SCHEMBL5394569 | 0.87 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL5394567 | 0.87 | NOS3 (0.45) | NOS3NOS1NOS2 | |
| SCHEMBL6602318 | 0.84 | NOS1 (0.58) | NOS3NOS1NOS2 | |
| SCHEMBL6602315 | 0.84 | NOS1 (0.58) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL5385359 | 0.83 | NOS1 (0.58) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL5385353 | 0.83 | NOS1 (0.58) | NOS3NOS1NOS2 | |
| SCHEMBL6598976 | 0.82 | NOS1 (0.56) | NOS3NOS1 | |
| SCHEMBL6598979 | 0.82 | NOS1 (0.56) | NOS3NOS1 | |
| SCHEMBL6600980 | 0.81 | NOS1 (0.52) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265891-B1 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | CONSEILS DE RECH SET D APPLIC (FR) | 2004-12-29 | — | — | EP | disclosed |
| EP-1265891-A2 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001068643-A2 | NOVEL LIPOIC ACID HETEROCYCLIC OR BENZENE DERIVATIVES, PREPARATION AND USE THEREOF AS MEDICINES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-09-20 | — | — | WO | disclosed |