Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988872 | 0.82 | NQO2 (0.66) | NQO2POLBKDM4ELMNACASP6 | |
| SCHEMBL6609095 | 0.81 | NR4A2 (0.48) | NQO2NR4A2POLBKDM4ELMNA | |
| SCHEMBL19009075 | 0.79 | NR4A2 (0.59) | NR4A2POLBLMNAL3MBTL1RAD52 | |
| SCHEMBL6602843 | 0.76 | KMT2A (0.58) | NR4A2POLBLMNAALDH1A1GLA | |
| SCHEMBL10266503 | 0.75 | NR4A2 (0.48) | NQO2NR4A2KDM4EL3MBTL1TERT | |
| SCHEMBL3235863 | 0.74 | NCF1 (0.63) | NQO2NR4A2POLBKDM4ELMNA | |
| SCHEMBL6846673 | 0.74 | CYP1A2 (0.57) | NQO2POLBKDM4ELMNACASP6 | |
| SCHEMBL6617291 | 0.74 | NQO2 (0.67) | NQO2POLBKDM4ENCF1ALDH1A1 | |
| SCHEMBL6613348 | 0.74 | NQO2 (0.75) | NQO2POLBKDM4ERAD52NCF1 | |
| Hydrochloric Acid SCHEMBL30579056 | 0.73 | NCF1 (0.61) | NQO2NR4A2POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |