Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.75 |
| ▸ | NCF1 | P14598 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617291 | 0.78 | NQO2 (0.67) | NQO2NCF1KDM4EALDH1A1GLA | |
| SCHEMBL5988872 | 0.77 | NQO2 (0.66) | NQO2NCF1KDM4EALDH1A1GLA | |
| SCHEMBL13015196 | 0.74 | PTGER4 (0.47) | NQO2NCF1ALDH1A1CYP2C19PTGER4 | |
| SCHEMBL11311817 | 0.74 | PTGER4 (0.50) | NQO2NCF1ALDH1A1CYP2C19RAD52 | |
| SCHEMBL6602282 | 0.74 | NQO2 (0.61) | NQO2NCF1KDM4EALDH1A1GLA | |
| SCHEMBL14587971 | 0.73 | MEN1 (0.71) | NQO2NCF1MEN1KMT2AGPR35 | |
| SCHEMBL19407604 | 0.73 | MEN1 (0.71) | NQO2NCF1MEN1KMT2AGPR35 | |
| SCHEMBL18290253 | 0.72 | NCF1 (0.81) | NQO2NCF1MEN1KMT2ACYP2C19 | |
| SCHEMBL855211 | 0.72 | PTGER4 (0.51) | NQO2NCF1KDM4EALDH1A1GAA | |
| SCHEMBL14587968 | 0.72 | NQO2 (0.71) | NQO2NCF1KDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |