Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601558 | 0.93 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1F10GRM2 | |
| SCHEMBL6601617 | 0.93 | ITGB3 (0.41) | ITGB3ITGA2BSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6601597 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BSIGMAR1F10GRM2 | |
| SCHEMBL6601119 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BSIGMAR1ADRA2AADRA2B | |
| SCHEMBL6601611 | 0.89 | ITGB3 (0.41) | ITGB3ITGA2BSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL6604918 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BSIGMAR1F10GRM2 | |
| SCHEMBL6605657 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BMAPTSIGMAR1KMT2A | |
| SCHEMBL6601751 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1HTR1AGRM2 | |
| SCHEMBL6600953 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1F10GRM2 | |
| SCHEMBL6600232 | 0.87 | ITGB3 (0.50) | ITGB3ITGA2BSMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-B1 | Adhesion receptor antagonists | MERCK PATENT GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |