Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | GNG2 | P59768 | 2/20 | 0.50 |
| ▸ | GNB1 | P62873 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608655 | 0.84 | HTT (0.59) | KMT2AMEN1MMP9GNG2GNB1 | |
| SCHEMBL6599966 | 0.81 | ABCG2 (0.53) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL6608651 | 0.80 | KDM4E (0.44) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL7763069 | 0.77 | GNG2 (0.81) | KMT2AMEN1MMP9GNG2GNB1 | |
| SCHEMBL13696892 | 0.77 | KMT2A (0.55) | KMT2AMEN1MMP9GNG2GNB1 | |
| SCHEMBL15624395 | 0.74 | KMT2A (0.51) | KMT2AMEN1MMP9GNG2GNB1 | |
| SCHEMBL25750389 | 0.73 | MAPK10 (0.57) | KMT2AMEN1MMP9MMP1ALDH1A1 | |
| SCHEMBL3651398 | 0.72 | MEN1 (0.57) | KMT2AMEN1MMP9GNG2GNB1 | |
| SCHEMBL3225408 | 0.72 | SMN1; SMN2 (0.79) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL23999812 | 0.72 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |