Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602513 | 0.84 | KMT2A (0.50) | HTTNQO2L3MBTL1MAPTNPC1 | |
| SCHEMBL9069887 | 0.82 | L3MBTL1 (0.67) | HTTLMNANQO2L3MBTL1MAPT | |
| SCHEMBL27777741 | 0.81 | DNMT1 (0.57) | L3MBTL1MAPTKMT2ATDP1GAA | |
| SCHEMBL21925700 | 0.80 | HTT (0.66) | HTTLMNAL3MBTL1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL1890853 | 0.80 | DNMT1 (0.56) | L3MBTL1MAPTKMT2ATDP1GAA | |
| SCHEMBL20605601 | 0.78 | HTT (0.52) | HTTLMNAL3MBTL1MAPTNPC1 | |
| SCHEMBL5989371 | 0.78 | TERT (0.60) | HTTLMNAL3MBTL1MAPTNPC1 | |
| SCHEMBL21853342 | 0.77 | ATM (0.67) | HTTLMNANQO2MAPTKMT2A | |
| SCHEMBL7763069 | 0.76 | GNG2 (0.81) | MAPTKMT2APOLBMAPK1MEN1 | |
| SCHEMBL13696892 | 0.76 | KMT2A (0.55) | LMNANQO2L3MBTL1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |