Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602887 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL1746604 | 0.74 | — | — | |
| SCHEMBL28719103 | 0.69 | — | — | |
| SCHEMBL7450284 | 0.68 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL27540587 | 0.68 | — | — | |
| SCHEMBL28758439 | 0.65 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL11422280 | 0.65 | — | — | |
| SCHEMBL1776008 | 0.64 | ALDH1A1 (0.34) | ALDH1A1TSHRHSD17B10PTGS2HPGD | |
| SCHEMBL15539 | 0.64 | — | — | |
| SCHEMBL10907875 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1062212-B1 | HETEROCYCLYL ANTHRACYCLINONE DERIVATIVES | PHARMACIA ITALIA SPA (IT) | 2004-05-12 | — | — | EP | disclosed |
| US-6316451-B1 | AMYLOIDOSIS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-11-13 | — | — | US | disclosed |
| EP-1062212-A1 | HETEROCYCLYL ANTHRACYCLINONE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999046253-A1 | HETEROCYCLYL ANTHRACYCLINONE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-09-16 | — | — | WO | disclosed |