Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548800 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13810444 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11174825 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3784058 | 0.76 | KMT2A (0.41) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15739721 | 0.76 | MEN1 (0.34) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2234056 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9256818 | 0.74 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL19384149 | 0.73 | KMT2A (0.39) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8548799 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1746604 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228399-A1 | TRICYCLIC USP1 INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |
| US-6028087-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| US-5726192-A | Platelet aggregation inhibiting compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |
| EP-0260744-B1 | (1H-IMIDAZOL-1-YLMETHYL) SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-12-16 | — | — | EP | disclosed |