Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.74 |
| ▸ | LIPC | P11150 | 1/20 | 0.74 |
| ▸ | LIPE | Q05469 | 1/20 | 0.74 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047919 | 0.85 | LPL (1.00) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL6601943 | 0.82 | LPL (0.72) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL7044266 | 0.81 | LPL (0.70) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL6603718 | 0.80 | LPL (0.69) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL7044283 | 0.79 | LPL (0.67) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL6604889 | 0.78 | LPL (0.72) | LPLLIPCLIPEFAAHMGLL | |
| Trifluoroacetic Acid SCHEMBL6601568 | 0.77 | LPL (0.47) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL6603513 | 0.76 | LPL (0.64) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL6600553 | 0.75 | LPL (0.62) | LPLLIPCLIPEFAAHMGLL | |
| SCHEMBL6801256 | 0.74 | NPC1 (0.76) | MLYCDALDH1A1MAPTKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |