Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPC | P11150 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6604365 | 0.90 | MGLL (0.46) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6601748 | 0.84 | FAAH (0.44) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6602539 | 0.81 | MAPT (0.45) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6599708 | 0.78 | LPL (0.46) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6600841 | 0.77 | MGLL (0.50) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6601589 | 0.77 | ABHD16A (0.47) | LPLLIPCLIPEABHD16AMGLL | |
| SCHEMBL6602780 | 0.77 | LPL (0.74) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6599045 | 0.74 | MGLL (0.48) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6601314 | 0.74 | MGLL (0.48) | LPLLIPCLIPEABHD16AMGLL | |
| Trifluoroacetic Acid SCHEMBL6601368 | 0.74 | MGLL (0.43) | LPLLIPCLIPEABHD16AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |