SCHEMBL660307

SCHEMBL660307

O=C1C=CC(=O)N1.O=C1CC(OC(=O)c2ccccc2)C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.43
CHRNA7 P36544 2/20 0.40
DDB1 Q16531 4/20 0.38
CRBN Q96SW2 4/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
HTR3A P46098 1/20 0.36
HTR3D Q70Z44 1/20 0.36
HTR3C Q8WXA8 1/20 0.36
F2 P00734 1/20 0.36
TSHR P16473 1/20 0.36
APOBEC3A P31941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068302 0.93 GAA (0.48) GAACHRNA7DDB1CRBNMEN1
Ammonia Solution, Strong SCHEMBL9774304 0.91 GAA (0.47) GAACHRNA7DDB1CRBNMEN1
SCHEMBL5320949 0.85 HTT (0.42) GAADDB1CRBNALDH1A1KDM4E
SCHEMBL5091923 0.80 TDP1 (0.45) GAADDB1CRBNKMT2ALMNA
SCHEMBL4556983 0.80 TDP1 (0.45) GAADDB1CRBNKMT2ALMNA
SCHEMBL8997420 0.78 HTT (0.35) GAACHRNA7DDB1CRBNLMNA
SCHEMBL1883113 0.77 CES2 (0.41) GAACHRNA7DDB1CRBNMEN1
SCHEMBL3675740 0.77 ALDH1A1 (0.48) GAAMEN1KMT2ALMNAALDH1A1
SCHEMBL44224 0.77 ALDH1A1 (0.45) GAADDB1CRBNALDH1A1KDM4E
SCHEMBL6510960 0.76 ALDH1A1 (0.45) GAADDB1CRBNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220308073-A1 BIOMARKER FOR ALZHEIMER'S DISEASE PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY (JP) 2022-09-29 US disclosed
US-20200150133-A1 BIOMARKER FOR ALZHEIMER'S DISEASE PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY (JP) 2020-05-14 US disclosed
EP-3633372-A1 BIOMARKER FOR ALZHEIMER'S DISEASE Public University Corporation Nagoya City University (JP) 2020-04-08 EP disclosed
US-20150260729-A1 SCHIZOPHRENIA MARKER SET AND ITS UTILIZATION NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2015-09-17 US disclosed
EP-2908134-A1 INTEGRATION DYSFUNCTION SYNDROME MARKER SET AND UTILIZATION THEREOF National University Corporation Nagoya University (JP) 2015-08-19 EP disclosed
CN-102597772-B 5.9 kDa peptide immunoassay method NITTO BOSEKI CO LTD 2014-08-20 CN disclosed
CN-102597772-A 5.9 kDa peptide immunoassay method NITTO BOSEKI CO LTD 2012-07-18 CN disclosed
CN-101240022-B Cell proliferation inhibitors containing anti-glypican 3 antibody CHUGAI PHARMACEUTICAL CO LTD 2012-07-18 CN disclosed
CN-102574927-A Hybridoma producing anti-methylated DNA antibody and use thereof SYSMEX CORP 2012-07-11 CN disclosed
US-20120046451-A1 ANTI-lgSF4 ANTIBODY AND UTILIZATION OF THE SAME INSTITUTE FOR ANTIBODIES CO., LTD. (JP) 2012-02-23 US disclosed
US-20090155778-A1 Mental Disorder-Related Gene and Use of the Same NATIONAL UNIVERSITY CORPORATION NAGOYA (JP) 2009-06-18 US disclosed
US-20090053243-A1 Anti-IgSF4 Antibody and Utilization of the Same INSTITUTE FOR ANTIBODIES CO., LTD (JP) 2009-02-26 US disclosed
US-20090004647-A1 Method of Judging Grade of Malignancy of Carcinoma Cell NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2009-01-01 US disclosed
CN-101240022-A Cell proliferation inhibitors containing anti-glypican 3 antibody CHUGAI PHARMACEUTICAL CO LTD (JP) 2008-08-13 CN disclosed
EP-1860119-A1 ANTI-IgSF4 ANTIBODY AND UTILIZATION OF THE SAME Institute for Antibodies Co., Ltd. (JP) 2007-11-28 EP disclosed
EP-1783231-A1 METHOD OF JUDGING GRADE OF MALIGNANCY OF CARCINOMA CELL Nagoya Industrial Science Research Institute (JP) 2007-05-09 EP disclosed
CN-1314803-C Cell growth inhibitor containing anti-glypican 3 antibody CHOONGWAE PHARMACUTICAL CORP (JP) 2007-05-09 CN disclosed
CN-1942581-A Antibody with osteoclast-related protein as target SANKYO CO (JP) 2007-04-04 CN disclosed
US-20060194268-A1 Method for measuring spinorphin MARUISHI PHARMACEUTICAL CO., LTD. (JP) 2006-08-31 US disclosed
CN-1688692-A Cell growth inhibitor containing anti-glypican 3 antibody CHOONGWAE PHARMACUTICAL CORP (JP) 2005-10-26 CN disclosed