Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603378 | 1.00 | FOLH1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6603366 | 1.00 | FOLH1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6602156 | 0.95 | ALDH1A1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6602158 | 0.95 | ALDH1A1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6602155 | 0.95 | ALDH1A1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6601552 | 0.94 | ALDH1A1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6601561 | 0.94 | ALDH1A1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6601557 | 0.94 | ALDH1A1 (0.38) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6977783 | 0.83 | KMT2A (0.43) | FOLH1KMT2AMEN1POLBTPSAB1 | |
| SCHEMBL6977780 | 0.83 | KMT2A (0.43) | FOLH1KMT2AMEN1POLBTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667772-B9 | TAXANES HAVING AN ALKYL SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNIV FLORIDA STATE (US) | 2004-08-04 | — | — | EP | disclosed |
| US-20030187061-A1 | Antitumor agnets; antileukemia agents | FLORIDA STATE UNIVERSITY | 2003-10-02 | — | — | US | disclosed |
| EP-0667772-B1 | TAXANES HAVING AN ALKYL SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | UNIV FLORIDA STATE (US) | 2003-05-14 | — | — | EP | disclosed |
| US-6521660-B2 | Anticancer, antitumor agents | FLORIDA STATE UNIVERSITY | 2003-02-18 | — | — | US | disclosed |
| US-20020147335-A1 | Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them | FLORIDA STATE UNIVERSITY | 2002-10-10 | — | — | US | disclosed |
| EP-0667772-A4 | TAXANES HAVING AN ALKYL SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNIV FLORIDA STATE (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0667772-A1 | TAXANES HAVING AN ALKYL SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FLORIDA STATE UNIVERSITY (US) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010997-A1 | TAXANES HAVING AN ALKYL SUBSTITUTED SIDE-CHAIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FLORIDA STATE UNIVERSITY (US) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187061-A1 | Antitumor agnets; antileukemia agents | MCL1, TP53, EWSR1 | FOLH1 3240/4885KMT2A 574/4885MEN1 959/4885 |
| US-20020147335-A1 | Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them | TOP2A, TOP2B, TUBB3 | FOLH1 1121/4885KMT2A 2652/4885MEN1 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.