Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362553 | 0.87 | CYP11B1 (0.43) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL10833120 | 0.86 | ALDH1A1 (0.43) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL6605761 | 0.85 | CYP11B1 (0.41) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL5206850 | 0.83 | RXRA (0.46) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL5211537 | 0.82 | RXRA (0.47) | KDM4EALDH1A1MAPTLMNARXRA | |
| SCHEMBL5209458 | 0.81 | LMNA (0.44) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL5212252 | 0.81 | MAPT (0.47) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL5209323 | 0.81 | MAPT (0.41) | KDM4EALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL7461993 | 0.80 | MAPT (0.40) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL5209417 | 0.79 | TP53 (0.41) | CYP11B1CYP11B2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699995-B1 | ALKYLATION AT 5-POSITION OF OXAZOLE BY REACTION WITH UNSATURATED COMPOUND IN PRESENCE OF ACID OR BASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1219610-B1 | PROCESS FOR THE PREPARATION OF OXAZOLE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1219610-A1 | PROCESS FOR THE PREPARATION OF OXAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |