Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605546 | 0.97 | NCF1 (0.57) | NCF1MAPTSMN1; SMN2ACHENPC1 | |
| SCHEMBL7474440 | 0.89 | NCF1 (0.61) | NCF1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL6201951 | 0.82 | MCHR1 (0.47) | MAPTSMN1; SMN2ACHEKDM4EAPP | |
| SCHEMBL7471109 | 0.81 | MAPT (0.59) | NCF1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3646902 | 0.80 | MAPT (0.47) | MAPTSMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL5530249 | 0.78 | SMN1; SMN2 (0.68) | NCF1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5024526 | 0.77 | KMT2A (0.52) | NCF1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6848360 | 0.77 | KMT2A (0.55) | MAPTSMN1; SMN2ACHEKMT2AMEN1 | |
| SCHEMBL15521695 | 0.77 | APP (0.57) | ACHEAPPBCHEGAA | |
| SCHEMBL6507114 | 0.76 | GAA (0.55) | SMN1; SMN2ACHEKMT2AMEN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |