Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | METAP1 | P53582 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.61 |
| ▸ | NCF1 | P14598 | 5/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23363541 | 0.82 | NCF1 (0.52) | SMN1; SMN2MAPTMETAP1KMT2ANPSR1 | |
| SCHEMBL2628839 | 0.78 | NPSR1 (0.58) | SMN1; SMN2MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL5065450 | 0.78 | NCF1 (0.88) | SMN1; SMN2MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL6605546 | 0.78 | NCF1 (0.57) | SMN1; SMN2MAPTNCF1LMNAGAA | |
| SCHEMBL6603576 | 0.78 | NCF1 (0.53) | SMN1; SMN2MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL1646189 | 0.77 | MEN1 (0.61) | SMN1; SMN2MAPTKMT2AMEN1ADRB1 | |
| SCHEMBL6125246 | 0.76 | NCF1 (0.75) | SMN1; SMN2MAPTMETAP1KMT2ANPSR1 | |
| SCHEMBL30511704 | 0.76 | NCF1 (0.97) | SMN1; SMN2MAPTMETAP1KMT2ANPSR1 | |
| SCHEMBL5242692 | 0.76 | KMT2A (0.71) | SMN1; SMN2MAPTKMT2ANPSR1MEN1 | |
| SCHEMBL12952781 | 0.76 | SIRT6 (0.71) | SMN1; SMN2MAPTKMT2AMEN1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197509-A1 | Compositions and methods for modulating gated ion channels | KCNN3, KCNN2, HCN3 | SMN1; SMN2 1321/4885MAPT 1841/4885METAP1 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.