Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603576 | 0.89 | NCF1 (0.53) | NCF1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL6605546 | 0.89 | NCF1 (0.57) | NCF1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7480479 | 0.80 | NCF1 (0.62) | NCF1ADRB2ALDH1A1HTR3EHTR3B | |
| SCHEMBL3949621 | 0.78 | NCF1 (0.68) | NCF1ADRB2ADRB1 | |
| SCHEMBL7471109 | 0.78 | MAPT (0.59) | NCF1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3646902 | 0.77 | MAPT (0.47) | NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL5205570 | 0.76 | ADRB1 (0.58) | ADRB1ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL30984739 | 0.76 | ADRB1 (0.58) | ADRB1ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL899675 | 0.76 | NCF1 (1.00) | NCF1ADRB2ADRB1ALDH1A1LMNA | |
| SCHEMBL30058969 | 0.76 | NCF1 (1.00) | NCF1ADRB2ADRB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228066-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032646-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |