Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933583 | 0.80 | LTA4H (0.56) | LTA4HMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL13210267 | 0.80 | ENPP3 (0.63) | LTA4HMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL17548467 | 0.80 | LTA4H (0.56) | LTA4HMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL15100535 | 0.79 | LTA4H (0.55) | LTA4HMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL13209803 | 0.79 | LTA4H (0.54) | LTA4HMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL8119166 | 0.79 | LTA4H (0.54) | LTA4HMAPTKDM4ENOTUMRAB9A | |
| SCHEMBL3636890 | 0.79 | LTA4H (0.54) | LTA4HMAPTKDM4ENOTUMRAB9A | |
| SCHEMBL2901258 | 0.77 | LTA4H (0.53) | LTA4HKDM4EMEN1KMT2AFBP1 | |
| SCHEMBL2056109 | 0.76 | ENPP3 (0.69) | LTA4HMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL15100543 | 0.76 | ENPP3 (0.65) | LTA4HMAPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204128-C | Process for preparing oxazole derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-06-01 | — | — | CN | disclosed |
| US-6699995-B1 | ALKYLATION AT 5-POSITION OF OXAZOLE BY REACTION WITH UNSATURATED COMPOUND IN PRESENCE OF ACID OR BASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1219610-B1 | PROCESS FOR THE PREPARATION OF OXAZOLE DERIVATIVES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1219610-A1 | PROCESS FOR THE PREPARATION OF OXAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |