Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603647 | 0.80 | LTA4H (0.81) | LTA4HALDH1A1POLBMAPTHPGD | |
| SCHEMBL13210267 | 0.80 | ENPP3 (0.63) | LTA4HALDH1A1MAPTFBP1ENPP3 | |
| SCHEMBL17548467 | 0.80 | LTA4H (0.56) | LTA4HALDH1A1POLBMAPTHPGD | |
| SCHEMBL13209803 | 0.79 | LTA4H (0.54) | LTA4HALDH1A1MAPTFBP1ENPP3 | |
| SCHEMBL8119166 | 0.79 | LTA4H (0.54) | LTA4HALDH1A1MAPTHPGDFBP1 | |
| SCHEMBL2901258 | 0.77 | LTA4H (0.53) | LTA4HMKNK1MKNK2FBP1MEN1 | |
| SCHEMBL24415640 | 0.76 | ENPP3 (0.69) | HSD17B1HSD17B2ALDH1A1POLBMAPT | |
| SCHEMBL29045675 | 0.76 | LTA4H (0.51) | LTA4HADORA2A | |
| SCHEMBL15100543 | 0.76 | ENPP3 (0.65) | LTA4HALDH1A1POLBMAPTHPGD | |
| SCHEMBL20391071 | 0.76 | FBP1 (0.41) | LTA4HHSD17B1HSD17B2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028193-A1 | COMPOUNDS INCLUDING PIMELIC ACID DERIVATIVES AS HDAC INHIBITORS | REPLIGEN CORPORATION (US) | 2010-03-11 | — | — | WO | disclosed |