Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602069 | 0.93 | SIGMAR1 (0.53) | SIGMAR1EBPTMEM97KDM4EGAA | |
| SCHEMBL5704645 | 0.84 | GAA (0.59) | KDM4EGAAMAPT | |
| SCHEMBL4041381 | 0.84 | KDM4E (0.59) | KDM4EGAAMAPT | |
| SCHEMBL188792 | 0.83 | GAA (0.50) | KDM4EGAAMAPT | |
| SCHEMBL22502366 | 0.83 | GAA (0.57) | SIGMAR1KDM4EGAAMAPT | |
| SCHEMBL22502189 | 0.82 | MAPT (0.66) | KDM4EGAAMAPT | |
| SCHEMBL3616464 | 0.82 | BIRC5 (0.54) | SIGMAR1KDM4EGAAMAPT | |
| SCHEMBL6200318 | 0.79 | GAA (0.46) | SIGMAR1KDM4EGAAMAPT | |
| SCHEMBL6604506 | 0.79 | GAA (0.43) | KDM4EGAAMAPT | |
| SCHEMBL1220219 | 0.78 | HTR7 (0.53) | KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |