Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15B | O15296 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599384 | 0.78 | ALDH1A1 (0.57) | ALOX15BL3MBTL1TDP1KCNH2ALDH1A1 | |
| SCHEMBL26964238 | 0.78 | ALOX15B (0.49) | ALOX15BL3MBTL1TDP1KCNH2KIF11 | |
| SCHEMBL10469438 | 0.76 | CYP3A4 (0.46) | ALOX15BL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL26964239 | 0.71 | MCL1 (0.42) | ALOX15BL3MBTL1TDP1KCNH2KIF11 | |
| SCHEMBL30553468 | 0.70 | ALOX15B (0.43) | ALOX15BL3MBTL1TDP1KCNH2KIF11 | |
| SCHEMBL30716464 | 0.68 | KMT2A (0.42) | ALOX15BL3MBTL1TDP1KCNH2ALDH1A1 | |
| SCHEMBL25382278 | 0.67 | NOTUM (0.39) | ALOX15BL3MBTL1KCNH2ALDH1A1NOTUM | |
| SCHEMBL28337522 | 0.66 | CDC7 (0.48) | ALOX15BL3MBTL1TDP1 | |
| SCHEMBL11060269 | 0.66 | TDP1 (0.47) | TDP1KIF11ALDH1A1KDM4ECYP11B2 | |
| SCHEMBL28003186 | 0.66 | NR1I2 (0.48) | KCNH2ALDH1A1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373217-A1 | 2-MERCAPTO-4,5-DIARYLIMIDAZOLE DERIVATIVES AND THE USE THEREOF AS CYCLOOXYGENASE INHIBITORS | Beiersdorf AG (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076951-A1 | 2-MERCAPTO-4,5-DIARYLIMIDAZOLE DERIVATIVES AND THE USE THEREOF AS CYCLOOXYGENASE INHIBITORS | BEIERSDORF AG (DE) | 2002-10-03 | — | — | WO | disclosed |