Sugi Predict

Sugi Predict / Compounds / SCHEMBL6603855

SCHEMBL6603855

SCHEMBL6603855

Cc1noc([C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)O[C@@H]2CCCNC2)n1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 8/20 0.44
▸ ZAP70 P43403 3/20 0.44
▸ CTSB P07858 2/20 0.40
▸ CTSS P25774 2/20 0.40
▸ CTSL P07711 1/20 0.40
▸ F2 P00734 1/20 0.39
▸ CTSK P43235 1/20 0.39
▸ EDNRA P25101 1/20 0.38
▸ PTPRB P23467 3/20 0.37
▸ FCER2 P06734 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6601069 0.91 SRC (0.46) SRCZAP70CTSBCTSSCTSL
SCHEMBL6600691 0.84 ZAP70 (0.46) SRCZAP70CTSBFCER2
SCHEMBL6600356 0.81 CTSS (0.59) SRCZAP70CTSBCTSSCTSL
SCHEMBL6600359 0.81 CTSS (0.59) SRCZAP70CTSBCTSSCTSL
SCHEMBL6600672 0.76 ZAP70 (0.46) SRCZAP70FCER2
SCHEMBL6600504 0.75 YAP1 (0.49) SRCZAP70CTSBCTSSCTSK
SCHEMBL6600505 0.75 YAP1 (0.49) SRCZAP70CTSBCTSSCTSK
Hydrochloric Acid SCHEMBL6600093 0.75 ZAP70 (0.46) SRCZAP70FCER2
SCHEMBL6600662 0.74 ZAP70 (0.47) SRCZAP70CTSBCTSSCTSL
SCHEMBL6600659 0.74 ZAP70 (0.47) SRCZAP70CTSBCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805816-B1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK AS (DK) 2004-07-28 — — EP claimed