Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.59 |
| ▸ | CTSK | P43235 | 4/20 | 0.59 |
| ▸ | CTSB | P07858 | 4/20 | 0.59 |
| ▸ | PTPRB | P23467 | 2/20 | 0.49 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600356 | 1.00 | CTSS (0.59) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL6602038 | 0.89 | CTSS (0.54) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL6602040 | 0.89 | CTSS (0.54) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL6600836 | 0.89 | CTSS (0.47) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL6600845 | 0.89 | CTSS (0.47) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL6600819 | 0.88 | CTSS (0.48) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL6600823 | 0.88 | CTSS (0.48) | CTSSCTSKCTSBPTPRBZAP70 | |
| SCHEMBL5960981 | 0.85 | ALDH1A1 (0.59) | CTSSCTSKCTSBPTPRBCTSL | |
| SCHEMBL7222255 | 0.85 | ALDH1A1 (0.59) | CTSSCTSKCTSBPTPRBCTSL | |
| SCHEMBL6600504 | 0.85 | YAP1 (0.49) | CTSSCTSKCTSBZAP70SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |