Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604313 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL1495919 | 0.81 | MEN1 (0.66) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| Benzene SCHEMBL6364361 | 0.81 | MEN1 (0.66) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6608386 | 0.79 | KDM4E (0.52) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6601697 | 0.77 | ALDH1A1 (0.70) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| Hydrogen Peroxide SCHEMBL28177611 | 0.77 | MAPT (0.53) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL6603038 | 0.77 | CYSLTR2 (0.54) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| Acetone SCHEMBL27714910 | 0.76 | KMT2A (0.49) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL887723 | 0.73 | MAPT (0.56) | KDM4EMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6603947 | 0.72 | KDM4C (0.56) | SMN1; SMN2KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |