Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.56 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495919 | 0.87 | MEN1 (0.66) | KDM4CMEN1KMT2AMAPTKDM4E | |
| Benzene SCHEMBL6364361 | 0.87 | MEN1 (0.66) | KDM4CMEN1KMT2AMAPTKDM4E | |
| SCHEMBL6608978 | 0.85 | KMT2A (0.65) | MEN1KMT2AL3MBTL1ALDH1A1HTT | |
| SCHEMBL6605120 | 0.83 | ALDH1A1 (0.53) | SCN7AKCNH2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6567209 | 0.80 | KDM4C (0.58) | KDM4CMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6603038 | 0.77 | CYSLTR2 (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6608386 | 0.76 | KDM4E (0.52) | SCN7AKCNH2MEN1KMT2AMAPT | |
| SCHEMBL5573093 | 0.75 | KMT2A (0.75) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7821754 | 0.74 | ALOX15 (0.68) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL14402628 | 0.73 | KMT2A (0.71) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |