Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603151 | 0.94 | MCHR1 (0.50) | TLR7PANK3MCHR1RAB9ASMN1; SMN2 | |
| SCHEMBL6604146 | 0.89 | MCHR1 (0.51) | TLR7PANK3MCHR1RAB9ASMN1; SMN2 | |
| SCHEMBL6603809 | 0.86 | MCHR1 (0.54) | TLR7MCHR1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6604722 | 0.86 | TLR7 (0.49) | TLR7PANK3SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6607034 | 0.85 | MAPT (0.50) | TLR7MCHR1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6603061 | 0.84 | NPSR1 (0.54) | MCHR1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6602784 | 0.83 | MAPT (0.45) | TLR7MCHR1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6602620 | 0.83 | ALDH1A1 (0.52) | TLR7MCHR1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL6603016 | 0.80 | MCHR1 (0.62) | TLR7MCHR1RAB9ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL6897971 | 0.79 | LMNA (0.58) | MCHR1RAB9ASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | claimed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | claimed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1102535-A4 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1102535-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000006085-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |