Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081198 | 0.91 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6594071 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6594082 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6081200 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6602382 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6079449 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6590313 | 0.81 | CTSV (0.44) | L3MBTL1 | |
| SCHEMBL6590323 | 0.81 | CTSV (0.44) | L3MBTL1 | |
| SCHEMBL6594141 | 0.80 | CYP19A1 (0.47) | MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6594148 | 0.80 | CYP19A1 (0.47) | MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |