Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607899 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL6723014 | 0.80 | L3MBTL1 (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL6723019 | 0.80 | L3MBTL1 (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL6723011 | 0.80 | L3MBTL1 (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL6607682 | 0.79 | PDE4D (0.46) | ALDH1A1KDM4ELMNAHSD17B10PDE4A | |
| SCHEMBL6604262 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAHSD17B10PDE4A | |
| Ethylene SCHEMBL7250284 | 0.77 | PDE4D (0.45) | ALDH1A1KDM4ELMNAHSD17B10PDE4A | |
| SCHEMBL7656780 | 0.77 | PDE4B (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL7656777 | 0.77 | PDE4B (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 | |
| SCHEMBL7656775 | 0.77 | PDE4B (0.41) | ALDH1A1KDM4ELMNAHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1110961-B1 | OXYGENIC HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO KK (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-6376535-B2 | PHOSPHODIESTERASE (PDE) INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1110961-A1 | OXYGENIC HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-06-27 | — | — | EP | disclosed |