Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723011 | 1.00 | L3MBTL1 (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6723014 | 1.00 | L3MBTL1 (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7656777 | 0.96 | PDE4B (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7656775 | 0.96 | PDE4B (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7656780 | 0.96 | PDE4B (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7669518 | 0.94 | L3MBTL1 (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7669521 | 0.94 | L3MBTL1 (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7669524 | 0.94 | L3MBTL1 (0.41) | L3MBTL1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6602217 | 0.89 | KDM4E (0.42) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL6602224 | 0.89 | KDM4E (0.42) | PDE4BPDE4APDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054197-A1 | Styrene derivatives and process for production thereof | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1362853-A1 | STYRENE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Kyowa Hakko Kogyo Co., Ltd (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054197-A1 | Styrene derivatives and process for production thereof | HSD3B1, SULT1A1, HSD3B2 | L3MBTL1 627/4885PDE4B 4492/4885PDE4A 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.