SCHEMBL6604569

SCHEMBL6604569

CCOC(=O)c1ccc(S(C)(=O)=O)c(OCCC2(C)N=NN=N2)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
NPC1 O15118 2/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
XBP1 P17861 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TLR9 Q9NR96 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
IKBKB O14920 1/20 0.37
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
CA12 O43570 3/20 0.35
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA6 P23280 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6604522 0.87
SCHEMBL6608753 0.87 IKBKB (0.32) IKBKBLMNA
SCHEMBL6608504 0.86 KMT2A (0.41) ALDH1A1NPC1MAPTMAPK1HTT
SCHEMBL6489572 0.76 GAA (0.41) ALDH1A1NPC1TP53MAPTXBP1
SCHEMBL6492895 0.75 PTGS2 (0.37) ALDH1A1NPC1TP53MAPTXBP1
SCHEMBL6481166 0.75 IKBKB (0.36) ALDH1A1NPC1TP53MAPTXBP1
SCHEMBL9375326 0.74 TSHR (0.47) ALDH1A1NPC1MAPTHSD17B10KMT2A
SCHEMBL7949545 0.73 TSHR (0.44) ALDH1A1NPC1TP53MAPTXBP1
SCHEMBL21179401 0.73 TSHR (0.46) ALDH1A1NPC1TP53MAPTXBP1
SCHEMBL6606589 0.72 ALDH1A1 (0.39) ALDH1A1NPC1MAPTMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed