Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028298 | 0.83 | MAPT (0.40) | LMNAAPAF1POLBMAPTALDH1A1 | |
| SCHEMBL6606932 | 0.82 | TSHR (0.42) | TSHRLMNAAPAF1POLBMEN1 | |
| SCHEMBL12955191 | 0.76 | MAPT (0.42) | LMNAAPAF1POLBMAPTALDH1A1 | |
| SCHEMBL1030032 | 0.76 | HTT (0.44) | LMNAAPAF1POLBMAPTALDH1A1 | |
| SCHEMBL12955255 | 0.76 | MAPT (0.40) | TSHRLMNAAPAF1POLBMAPT | |
| SCHEMBL27739426 | 0.71 | MAPT (0.40) | LMNAAPAF1POLBMAPTALDH1A1 | |
| SCHEMBL27110118 | 0.71 | GAA (0.40) | TSHRLMNAAPAF1POLBMAPT | |
| SCHEMBL15746137 | 0.70 | GAA (0.42) | LMNAAPAF1POLBMAPTALDH1A1 | |
| SCHEMBL9608890 | 0.69 | GAA (0.44) | LMNAAPAF1POLBMAPTALDH1A1 | |
| SCHEMBL25303381 | 0.69 | KDM4E (0.51) | LMNAAPAF1POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219173-B1 | INSECTICIDES AND ACARICIDES | AGRO KANESHO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-20030191171-A1 | Pyrazolyl compound | AGRO-KANESHO CO., LTD. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | AGRO-KANESHO CO., LTD. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1219173-A1 | INSECTICIDAL AND ACARICIDAL AGENTS | Agro-Kanesho Co., Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | GSTO1, CBR3, CBR1 | TSHR 1972/4885LMNA 2648/4885APAF1 1261/4885 |
| US-20030191171-A1 | Pyrazolyl compound | GSTO1, CBR3, GSTM1 | TSHR 1212/4885LMNA 2609/4885APAF1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.