Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604745 | 0.82 | TSHR (0.41) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL2824324 | 0.81 | KDM4E (0.48) | ALDH1A1FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2827976 | 0.76 | LMNA (0.46) | TSHRALDH1A1L3MBTL1FFAR1DAO | |
| SCHEMBL20353295 | 0.76 | SMN1; SMN2 (0.43) | TSHRALDH1A1L3MBTL1FFAR1DAO | |
| SCHEMBL4085587 | 0.75 | HTT (0.47) | TSHRALDH1A1L3MBTL1FFAR1DAO | |
| SCHEMBL12492462 | 0.75 | SMN1; SMN2 (0.42) | TSHRALDH1A1L3MBTL1FFAR1DAO | |
| SCHEMBL24589257 | 0.72 | SMN1; SMN2 (0.51) | TSHRALDH1A1FFAR1DAOMEN1 | |
| SCHEMBL2827324 | 0.71 | KDM4E (0.51) | ALDH1A1L3MBTL1FFAR1DAOMEN1 | |
| SCHEMBL21576140 | 0.70 | P2RX7 (0.48) | TSHRALDH1A1L3MBTL1FFAR1DAO | |
| SCHEMBL2828555 | 0.70 | SMN1; SMN2 (0.38) | TSHRALDH1A1L3MBTL1FFAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219173-B1 | INSECTICIDES AND ACARICIDES | AGRO KANESHO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-20030191171-A1 | Pyrazolyl compound | AGRO-KANESHO CO., LTD. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | AGRO-KANESHO CO., LTD. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1219173-A1 | INSECTICIDAL AND ACARICIDAL AGENTS | Agro-Kanesho Co., Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | GSTO1, CBR3, CBR1 | TSHR 1972/4885ALDH1A1 330/4885L3MBTL1 235/4885 |
| US-20030191171-A1 | Pyrazolyl compound | GSTO1, CBR3, GSTM1 | TSHR 1212/4885ALDH1A1 239/4885L3MBTL1 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.