Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601633 | 0.85 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL6604194 | 0.83 | PSEN1 (0.33) | — | |
| SCHEMBL6604651 | 0.83 | PSEN1 (0.33) | — | |
| SCHEMBL7009758 | 0.83 | — | — | |
| SCHEMBL6205886 | 0.81 | — | — | |
| SCHEMBL6588819 | 0.79 | KCNH2 (0.33) | HTR6PTGDR2KCNH2 | |
| SCHEMBL6604880 | 0.78 | CTSK (0.39) | — | |
| SCHEMBL7428571 | 0.76 | RPLP1 (0.33) | PTGDR2KCNH2 | |
| SCHEMBL5970799 | 0.76 | HTR6 (0.34) | HTR6PTGDR2KCNH2 | |
| SCHEMBL6599127 | 0.75 | PBK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392657-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-1392657-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003053331-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |