Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602905 | 0.81 | GFER (0.52) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6604929 | 0.80 | GRIA1 (0.46) | ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL6605320 | 0.70 | MAPT (0.49) | MAPTSMN1; SMN2 | |
| SCHEMBL6603376 | 0.68 | HPSE (0.46) | ALDH1A1MAPTLMNANPSR1MEN1 | |
| SCHEMBL4921644 | 0.67 | MAPT (0.55) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1138185 | 0.67 | MAPT (0.55) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6603312 | 0.67 | KCNMA1 (0.38) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL27272698 | 0.67 | MAPT (0.67) | GFERALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL16697818 | 0.66 | MAPT (0.65) | GFERALDH1A1MAPTLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL9382197 | 0.66 | MAPT (0.66) | GFERALDH1A1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020453-B1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERIVATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6348461-B1 | CENTRAL NERVOUS SYSTEM ANTAGONIST WITH HETEROCYCLIC SUBSTITUENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1020453-A1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERI VATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |