Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 12/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604939 | 0.81 | GFER (0.52) | GFERMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6607136 | 0.79 | ALDH1A1 (0.43) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6607045 | 0.77 | ALDH1A1 (0.43) | MAPTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6607856 | 0.76 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6602596 | 0.75 | ALDH1A1 (0.41) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8369082 | 0.73 | PPARG (0.43) | MAPTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6604726 | 0.72 | ALDH1A1 (0.38) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6604072 | 0.72 | ALDH1A1 (0.46) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6602007 | 0.69 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6603316 | 0.69 | ALDH1A1 (0.45) | MAPTLMNAALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020453-B1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERIVATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6348461-B1 | CENTRAL NERVOUS SYSTEM ANTAGONIST WITH HETEROCYCLIC SUBSTITUENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1020453-A1 | 6,7-ASYMMETRICALLY DISUBSTITUTED QUINOXALINECARBOXYLIC ACID DERI VATIVES, ADDITION SALTS THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |