Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MBTPS1 | Q14703 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2262428 | 0.87 | MEN1 (0.67) | MEN1KMT2AGAAKDM4ELMNA | |
| SCHEMBL5889435 | 0.75 | MEN1 (0.69) | MEN1KMT2ASLC6A2SLC6A4GAA | |
| SCHEMBL19554727 | 0.75 | MEN1 (0.68) | MEN1KMT2AGAAKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL28528536 | 0.74 | MEN1 (0.67) | MEN1KMT2AGAAKDM4ELMNA | |
| SCHEMBL12449803 | 0.73 | ALDH1A1 (0.52) | MEN1KMT2ACYP3A4CNR2KDM4E | |
| SCHEMBL5309035 | 0.71 | MEN1 (0.51) | MEN1KMT2ACNR2LMNACCR1 | |
| SCHEMBL15745972 | 0.71 | AKT1 (0.53) | KMT2ACYP2D6GAALMNA | |
| SCHEMBL8791707 | 0.70 | MEN1 (0.61) | MEN1KMT2AKDM4ELMNA | |
| SCHEMBL4189434 | 0.70 | LMNA (0.50) | MEN1KMT2ACYP3A4LMNA | |
| SCHEMBL12575203 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2ASLC6A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181278-B1 | CYCLIC AMINE DERIVATIVES AND THEIR USES | BRISTOL MYERS SQUIBB PHARMA RE (US) | 2004-09-29 | — | — | EP | disclosed |