Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640308 | 0.85 | IDO1 (0.43) | CYP1A2HSD17B10ESR1ESR2 | |
| SCHEMBL668564 | 0.81 | ALDH1A1 (0.39) | GPR84CYP1A2MCL1ACMSDALDH1A1 | |
| SCHEMBL25252116 | 0.80 | ALDH1A1 (0.40) | GPR84CYP1A2MCL1ACMSDALDH1A1 | |
| SCHEMBL5680350 | 0.79 | MAOA (0.42) | GPR84CYP1A2ALDH1A1HPGDTSHR | |
| SCHEMBL2496705 | 0.79 | HSP90AA1 (0.42) | CYP1A2HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL28676386 | 0.77 | KDM4E (0.38) | GPR84CYP1A2MCL1ACMSDALDH1A1 | |
| SCHEMBL668633 | 0.77 | ALDH1A1 (0.40) | GPR84MCL1ACMSDALDH1A1HPGD | |
| SCHEMBL10670045 | 0.77 | BACE1 (0.45) | GPR84ALDH1A1HPGDHSD17B10ESR1 | |
| SCHEMBL6942856 | 0.77 | BACE1 (0.45) | GPR84ALDH1A1HPGDHSD17B10ESR1 | |
| SCHEMBL7200530 | 0.74 | ESR2 (0.45) | GPR84CYP1A2ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | claimed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | claimed |
| US-5516577-A | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| EP-0569827-A2 | Organic electroluminescence device | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |