Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607041 | 0.94 | MAPT (0.52) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL6603998 | 0.93 | MAPT (0.51) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL6604019 | 0.92 | MAPT (0.50) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL6604036 | 0.92 | L3MBTL1 (0.55) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL6603127 | 0.90 | MAPT (0.47) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL6603307 | 0.86 | LMNA (0.54) | KMT2AL3MBTL1MEN1RAB9ANPC1 | |
| SCHEMBL6602172 | 0.86 | L3MBTL1 (0.49) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| SCHEMBL6604600 | 0.85 | ABCG2 (0.52) | MAPTKMT2AL3MBTL1MEN1KDM4E | |
| Hydrochloric Acid SCHEMBL7652840 | 0.85 | LMNA (0.53) | KMT2AL3MBTL1MEN1RAB9ANPC1 | |
| SCHEMBL6604008 | 0.85 | ALDH1A1 (0.51) | MAPTKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922036-B1 | ARYLALKANOYL PYRIDAZINES | MERCK PATENT GMBH (DE) | 2004-03-24 | — | — | EP | disclosed |