Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965956 | 0.84 | SMN1; SMN2 (0.46) | TDP1AGERMTNR1ASMN1; SMN2LMNA | |
| SCHEMBL376141 | 0.78 | LMNA (0.52) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4667136 | 0.73 | MEN1 (0.45) | MEN1KMT2ACES2CES1 | |
| SCHEMBL19949104 | 0.71 | KMT2A (0.45) | TDP1MEN1KMT2A | |
| SCHEMBL17801922 | 0.70 | TSHR (0.55) | TDP1MEN1KMT2ASMN1; SMN2SNCA | |
| SCHEMBL2468579 | 0.70 | LMNA (0.32) | LMNA | |
| SCHEMBL30481859 | 0.69 | IDO1 (0.36) | TDP1PKMNR3C1METAP2CES2 | |
| SCHEMBL6412500 | 0.69 | LMNA (0.49) | TDP1MEN1KMT2ALMNA | |
| SCHEMBL3127194 | 0.69 | LOXL2 (0.51) | TDP1SMN1; SMN2LMNA | |
| SCHEMBL7609127 | 0.67 | ALDH1A1 (0.50) | TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395251-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002100818-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |