Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14974686 | 0.89 | RAB9A (0.48) | MEN1KMT2APKMRAB9ANPC1 | |
| SCHEMBL6586108 | 0.81 | MEN1 (0.42) | MEN1KMT2AALDH1A1TSHRPKM | |
| SCHEMBL13543523 | 0.78 | RAB9A (0.54) | MEN1KMT2APKMRAB9ANPC1 | |
| SCHEMBL6609665 | 0.75 | HSD11B1 (0.47) | MEN1KMT2AALDH1A1TSHRRAB9A | |
| SCHEMBL17933568 | 0.74 | MAPT (0.70) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30189629 | 0.72 | SMN1; SMN2 (0.57) | MEN1KMT2AALDH1A1PKMRAB9A | |
| SCHEMBL459471 | 0.72 | SMN1; SMN2 (0.57) | MEN1KMT2AALDH1A1PKMRAB9A | |
| SCHEMBL28236281 | 0.72 | SMN1; SMN2 (0.49) | ALDH1A1PKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4485011 | 0.72 | MAPT (0.68) | MEN1KMT2AALDH1A1TSHRPKM | |
| SCHEMBL5458651 | 0.70 | SMN1; SMN2 (0.59) | MEN1KMT2AALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |