Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606536 | 1.00 | KDM4E (0.55) | KDM4EEGFRCYP2A6HSD17B10ALDH5A1 | |
| SCHEMBL10846493 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1ENPP2FDPSKMT2A | |
| SCHEMBL3144474 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1ENPP2FDPSKMT2A | |
| SCHEMBL11125760 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1ENPP2FDPSKMT2A | |
| SCHEMBL2279519 | 0.79 | ENPP2 (0.56) | KDM4ECYP2A6ALDH1A1ENPP2FDPS | |
| SCHEMBL2279521 | 0.79 | ENPP2 (0.56) | KDM4ECYP2A6ALDH1A1ENPP2FDPS | |
| SCHEMBL3715295 | 0.78 | CYP2A6 (0.44) | KDM4EEGFRCYP2A6HSD17B10ALDH5A1 | |
| SCHEMBL3715296 | 0.78 | CYP2A6 (0.44) | KDM4EEGFRCYP2A6HSD17B10ALDH5A1 | |
| SCHEMBL2986380 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1 | |
| SCHEMBL3450554 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1ENPP2FDPSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078768-B1 | PROCESS FOR THE CATALYTIC PD ARYLATION OF OLEFINES WITH ARYL HALOGENIDES | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | claimed |
| US-4564479-A | PALLADIUM COMPOUND, PHOSPHORUS OR ARSENIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1986-01-14 | — | — | US | claimed |
| EP-0999835-A4 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | ONTOGEN CORP (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-0999835-A1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | Ontogen Corporation (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999002155-A1 | IMIDAZOLE DERIVATIVES AS MDR MODULATORS | ONTOGEN CORPORATION (US) | 1999-01-21 | — | — | WO | disclosed |
| US-4564479-A | PALLADIUM COMPOUND, PHOSPHORUS OR ARSENIC COMPOUND | CIBA-GEIGY CORPORATION (US) | 1986-01-14 | — | — | US | disclosed |
| US-4366189-A | WHITENERS | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |
| US-4346016-A | FOR NATURAL AND SYNTHETIC POLYMERS | CIBA-GEIGY CORPORATION (US) | 1982-08-24 | — | — | US | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |