Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279521 | 1.00 | ENPP2 (0.56) | ENPP2ALDH1A1UNGKDM4ECYP2A6 | |
| SCHEMBL24157696 | 0.80 | ENPP2 (0.56) | ENPP2ALDH1A1KDM4EFDPSFBP1 | |
| SCHEMBL24158105 | 0.80 | ENPP2 (0.56) | ENPP2ALDH1A1KDM4EFDPSFBP1 | |
| SCHEMBL6606539 | 0.79 | KDM4E (0.55) | ENPP2ALDH1A1KDM4ECYP2A6FDPS | |
| SCHEMBL6606536 | 0.79 | KDM4E (0.55) | ENPP2ALDH1A1KDM4ECYP2A6FDPS | |
| SCHEMBL13503132 | 0.78 | ENPP2 (0.50) | ENPP2ALDH1A1KDM4EFDPSFBP1 | |
| Isophthalic Dicarboxaldehyde SCHEMBL4952540 | 0.78 | ALDH1A1 (0.67) | ALDH1A1UNGKDM4ECYP2A6FBP1 | |
| Isophthalic Dicarboxaldehyde SCHEMBL180566 | 0.78 | ALDH1A1 (0.67) | ALDH1A1UNGKDM4ECYP2A6FBP1 | |
| SCHEMBL18002842 | 0.77 | FBP1 (0.58) | FBP1MAOAMAOB | |
| SCHEMBL11174940 | 0.76 | ENPP2 (0.56) | ENPP2ALDH1A1KDM4EFDPSMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059668-B2 | LSD1 inhibitors | Mirati Therapeutics, Inc. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20170129857-A1 | LSD1 Inhibitors | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | US | disclosed |
| US-20170129857-A1 | LSD1 Inhibitors | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | US | disclosed |
| WO-2017079476-A1 | LSD1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | WO | disclosed |
| WO-2017079476-A1 | LSD1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | WO | disclosed |
| US-20170129857-A1 | LSD1 Inhibitors | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | US | disclosed |
| US-7989478-B2 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |
| US-7691883-B2 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-06 | — | — | US | disclosed |
| US-7691883-B2 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-06 | — | — | US | disclosed |
| US-20070265228-A1 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20070265228-A1 | Cinnamoyl compound and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-11-15 | — | — | US | disclosed |
| US-20060211680-A1 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1671961-A1 | CINNAMOYL COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
| EP-1671948-A1 | CINNAMOYL COMPOUND AND USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211680-A1 | decreases expression of a Type I collage gene in a tissue to induce a reduction in accumulation of collagen and thereby improves tissue fibrosis | COL2A1, COL1A1, COL14A1 | ENPP2 1315/4885ALDH1A1 576/4885UNG 3128/4885 |
| US-20170129857-A1 | LSD1 Inhibitors | KDM1B, KDM1A, KDM3A | ENPP2 1115/4885ALDH1A1 364/4885UNG 564/4885 |
| US-10059668-B2 | LSD1 inhibitors | KDM1B, KDM1A, KDM3A | ENPP2 1115/4885ALDH1A1 364/4885UNG 564/4885 |
| US-20070265228-A1 | Cinnamoyl compound and use of the same | NPC1, CES2, CYP51A1 | ENPP2 2494/4885ALDH1A1 83/4885UNG 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.