Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609665 | 0.84 | HSD11B1 (0.47) | HTTALDH1A1HPGDHSD17B10ALDH3A1 | |
| SCHEMBL4812770 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL11050599 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL3545668 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL4951882 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL8484861 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL4954181 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL8483813 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL4815560 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2CYP24A1CYP1A2CYP3A4 | |
| SCHEMBL6607741 | 0.71 | MEN1 (0.47) | ALDH1A1CYP24A1GAAPOLBKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787561-B1 | HYPERLIPIDEMIA, ARTERIOSCLEROSIS; ORAL ADMINISTRATION; SUPPRESSING THE FORMING OF MACROPHAGES | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1197493-B1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO LTD (JP) | 2004-03-24 | — | — | EP | disclosed |
| EP-1197493-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |